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Washington University St. Louis
Cytokine-Induced Memory-Like NK Cells For Adoptive Immunotherapy of AML.
Recent scientific advances have shown that cytokine activation results in cytokine-induced memory-like (CIML) NK cells with superior anti-leukemia activity. We will translate CIML NK cells into a first-in-human clinical trial for acute myeloid leukemia patients. Correlative studies will evaluate CIML NK cells expansion, survival, activation, and function in patients.