Grant A. Challen, PhD


Washington University St. Louis

The Role of Mutations in Epigenetic Regulators in Myeloid Leukemia

Cure rates for AML patients have not substantially improved in the last 40 years. To keep pace with the genomics revolution, the focus of this project is to develop model systems that more closely resemble the natural history of cancer to understand how different mutations co-operate to cause AML.